Yao W Z, Zhoa M W, Han R X
Division of Respiratory Medicine, Third Hospital, Beijing Medical University.
Zhonghua Jie He He Hu Xi Za Zhi. 1994 Aug;17(4):220-2, 254.
PD25-V50 as a judgement of bronchial provocation test was compared with PD20-FEV1. Both PD25-V50 and PD20-FEV1 showed linear correlation, but PD25-V50 was more sensitive than PD20-FEV1 for the diagnosis of bronchial asthma, and had higher specificity and sensitivity, and lower false-negative and false-positiverate. Moreover PD25-V50 provided the advantages of shorter period of histamine provocation and lower dose of inhaled histamine, so that avoided the side effects of higher dose of histamine.