Ying S, Cheng J
Department of Neurobiology, Shanghai Medical University.
Zhen Ci Yan Jiu. 1994;19(1):29-32.
In the model of gerbil of acute global ischemia and reperfusion, we studied the effects of electro-acupuncture (EA) on total power of EEG at different periods of global ischemia and reperfusion. The "Fengfu" (GV 16) and "Jinsuo" (GV 8) points were stimulated by electrical pulse with frequency 7 Hz and intensity of 5-6 mA for 30 min. Recording was made before ischemia and 0 min, 15 min, 30 min, 60 min, 120 min and 240 min after reperfusion respectively. The results were as follows: 1. In the control group, after 10 min of ischemia, the amplitude of EEG was severely inhibited, even became flatten, and the total power of EEG was significantly decreased to 1.41 + 1.29%. After reperfusion, the recovery of total power was very slow. The peak level of recovery occurred at 120 min following reperfusion was 27.39 + 11.31%. 2. In comparison with the control group, the EA remarkably improved the recovery of EEG after ischemia and reperfusion. The recovery of total power was 71.45 + 16.46% (P < 0.01), and 75.27 + 18.43% (P < 0.01) at 120 min and 240 min after reperfusion respectively. These results strongly indicate that EA could reduce the EEG inhibition during global ischemia and improve the recovery after reperfusion.
在沙土鼠急性全脑缺血再灌注模型中，我们研究了电针对全脑缺血及再灌注不同时期脑电图总功率的影响。采用频率为7Hz、强度为5 - 6mA的电脉冲刺激“风府”（GV 16）和“金索”（GV 8）穴30分钟。分别在缺血前及再灌注后0分钟、15分钟、30分钟、60分钟、120分钟和240分钟进行记录。结果如下：1. 对照组在缺血10分钟后，脑电图波幅受到严重抑制，甚至变平，脑电图总功率显著下降至1.41 + 1.29%。再灌注后，总功率恢复非常缓慢。再灌注后120分钟时恢复的峰值水平为27.39 + 11.31%。2. 与对照组相比，电针显著改善了缺血及再灌注后脑电图的恢复。再灌注后120分钟和240分钟时总功率的恢复率分别为71.45 + 16.46%（P < 0.01）和75.27 + 18.43%（P < 0.01）。这些结果有力地表明，电针可减轻全脑缺血期间的脑电图抑制，并改善再灌注后的恢复情况。
