Parham G, Heppard M C, DiSaia P J
Department of Obstetrics and Gynecology, University of Arkansas for Medical Sciences, Little Rock 72205.
Gynecol Oncol. 1994 Dec;55(3 Pt 1):469-72. doi: 10.1006/gyno.1994.1325.
Adenocarcinoma originating in the endocervix may remain occult for many years. This may result in an extension to the uterine isthmus and corpus, with subsequent dissemination along the pathways of spread of uterine carcinoma, including metastasis to the ovaries. The patient described in this report had a bulky stage Ib cervical adenocarcinoma with metastasis in a transposed ovary. The metastasis was noted 6 months following postoperative external pelvic irradiation. The sequence of events strongly suggests that microscopic ovarian disease was present at the time of the original surgery. Other cases have been reported; however, the exact incidence is difficult to determine. The current literature on this subject is reviewed and recommendations are made for evaluation and treatment.
起源于子宫颈管内膜的腺癌可能多年隐匿不显。这可能导致癌肿扩展至子宫峡部和子宫体,随后沿子宫癌的扩散途径播散,包括转移至卵巢。本报告中描述的患者患有体积较大的Ib期宫颈腺癌,且转移至移位的卵巢。转移灶在术后盆腔外照射6个月后被发现。这一系列事件强烈提示在初次手术时就已存在微小的卵巢病变。其他病例也有报道;然而,确切的发病率难以确定。本文对该主题的现有文献进行了综述,并对评估和治疗提出了建议。