Maw A R, Bawden R
Department of Otolaryngology, Bristol Royal Infirmary, United Kingdom.
Int J Pediatr Otorhinolaryngol. 1994 Nov;30(3):189-204. doi: 10.1016/0165-5876(94)90060-4.
Two hundred and twenty two children with persistent bilateral otitis media with effusion (OME) were treated with unilateral ventilation tube insertion and no treatment to the contralateral ear. The tympanic membrane changes in the operated and unoperated ears were compared during a 12 year follow-up. Segmental atrophy resulted from tube insertion whereas minor scarring and thickening of the pars tensa was related to the middle ear condition. Eight three percent of untreated ears and 85% of those treated with tubes did not develop atelectasis. Sixty percent of untreated ears and 64% of treated ears did not develop attic retraction. Very few cases (1.5 and 2%) in untreated and treated ears, respectively developed severe atelectasis. The overall duration of OME was assessed from the pre-operative history of hearing loss, the 3 month period of pre-operative observation and the post-operative time with effusion. There is a relationship between duration of the disease and development of both atelectasis and attic retraction.
222名双侧持续性中耳积液（OME）患儿接受了单侧鼓膜置管术，对侧耳朵未进行治疗。在12年的随访期间，比较了手术耳和未手术耳的鼓膜变化。置管导致节段性萎缩，而紧张部的轻微瘢痕形成和增厚与中耳状况有关。83%的未治疗耳和85%的置管治疗耳未发生肺不张。60%的未治疗耳和64%的治疗耳未发生上鼓室回缩。未治疗耳和治疗耳中分别只有极少数病例（1.5%和2%）发生了严重肺不张。OME的总病程根据术前听力损失病史、术前3个月的观察期以及术后积液时间进行评估。疾病持续时间与肺不张和上鼓室回缩的发生之间存在关联。
