枯草芽孢杆菌中KinA、KinB和KinC在芽孢形成起始过程中的不同作用。
Different roles for KinA, KinB, and KinC in the initiation of sporulation in Bacillus subtilis.
作者信息
LeDeaux J R, Yu N, Grossman A D
机构信息
Department of Biology, Massachusetts Institute of Technology, Cambridge 02139.
出版信息
J Bacteriol. 1995 Feb;177(3):861-3. doi: 10.1128/jb.177.3.861-863.1995.
Abstract
Activation (phosphorylation) of the transcription factor encoded by spo0A is essential for the initiation of sporulation in Bacillus subtilis. At least three histidine protein kinases are involved in the phosphorylation of Spo0A. Under some growth conditions, KinA was the primary kinase, but under other conditions, KinB had the more critical role. KinC was required for the initial activation of Spo0A, even in the presence of KinA and KinB.
摘要
由spo0A编码的转录因子的激活（磷酸化）对于枯草芽孢杆菌中芽孢形成的起始至关重要。至少有三种组氨酸蛋白激酶参与Spo0A的磷酸化。在某些生长条件下，KinA是主要激酶，但在其他条件下，KinB发挥更关键的作用。即使存在KinA和KinB，Spo0A的初始激活也需要KinC。
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