Lozada-Nur F, Robinson J, Regezi J A
Department of Stomatology, University of California San Francisco.
Oral Surg Oral Med Oral Pathol. 1994 Nov;78(5):599-602. doi: 10.1016/0030-4220(94)90171-6.
Hairy leukoplakia was first described in association with HIV infection. Today hairy leukoplakia has come to represent a sign of immunosuppression and not just of HIV infection. Although molecular mechanisms have not been fully elucidated, Epstein-Barr virus appears to play a significant role in its etiopathogenesis. We present four cases that illustrate that HL may be seen in non-HIV and nonimmunocompromised patients. The use of high potency topical steroids for the treatment of oral vesiculoerosive diseases seems to have been a contributing factor in two of these cases.
毛状白斑最初是在与HIV感染相关的情况下被描述的。如今，毛状白斑已成为免疫抑制的一种标志，而不仅仅是HIV感染的标志。尽管其分子机制尚未完全阐明，但爱泼斯坦-巴尔病毒似乎在其发病机制中起着重要作用。我们呈现了4例病例，这些病例表明毛状白斑可见于非HIV感染和非免疫功能低下的患者。在其中2例病例中，使用高效局部类固醇治疗口腔水疱糜烂性疾病似乎是一个促成因素。
