Meehan S, Davis V, Brahim J S
National Institute of Dental Research, Clinical Investigations and Patient Care Branch.
Oral Surg Oral Med Oral Pathol. 1994 Nov;78(5):603-6. doi: 10.1016/0030-4220(94)90172-4.
Rhabdomyosarcoma is a neoplasm composed of striated muscle. One of the most common types of soft tissue mesenchymal tumors in infants, children, and adolescents, rhabdomyosarcoma was considered an almost uniformly fatal cancer as recently as 30 years ago. Presently a multimodal approach consisting of surgery, radiation, and chemotherapy has significantly improved the outlook for the patient with rhabdomyosarcoma. This article presents a case of intraoral rhabdomyosarcoma that was initially poorly controlled because of a lack of patient compliance. After proper treatment, the cancer went into remission. The patient remained cancer-free for 7 years, albeit with significant morbidity. This case demonstrates the significantly improved prognosis achieved with multimodal therapy.
横纹肌肉瘤是一种由横纹肌组成的肿瘤。它是婴儿、儿童和青少年中最常见的软组织间叶性肿瘤类型之一，就在30年前，横纹肌肉瘤还被认为是一种几乎无一例外会致命的癌症。目前，由手术、放疗和化疗组成的多模式治疗方法已显著改善了横纹肌肉瘤患者的预后。本文介绍了一例口腔内横纹肌肉瘤病例，该病例最初因患者依从性差而控制不佳。经过适当治疗后，癌症进入缓解期。患者7年无癌，但有明显的并发症。该病例证明了多模式治疗可显著改善预后。
