Schölmerich J
Klinik und Poliklinik für Innere Medizin I, Universität Regensburg.
Praxis (Bern 1994). 1995 Jan 10;84(2):29-33.
Treatment of chronic inflammatory bowel disease can be divided into therapy of active disease, strategies in chronic, active disease and prevention of relapse. In Crohn's disease as well as in ulcerative colitis steroids are of major importance in the treatment of active disease. For ulcerative colitis 5-aminosalicylic acid is used in addition, in particular with mild or moderate disease. It is used for prevention of relapse in chronic inflammatory bowel disease. Immunosuppressive drugs are indicated in chronic, active Crohn's disease, while surgery is important in ulcerative colitis. New developments are predominantly related to nonsystemic steroids, which are studied in different modalities of galenic preparations.
慢性炎症性肠病的治疗可分为活动性疾病的治疗、慢性活动性疾病的治疗策略以及复发的预防。在克罗恩病和溃疡性结肠炎中，类固醇在活动性疾病的治疗中具有重要作用。对于溃疡性结肠炎，还会使用5-氨基水杨酸，尤其是在病情轻度或中度时。它用于慢性炎症性肠病复发的预防。免疫抑制药物适用于慢性活动性克罗恩病，而手术在溃疡性结肠炎中很重要。新进展主要与非全身性类固醇有关，这些类固醇正在不同剂型的药剂中进行研究。
