[Body adaptive reactions to a change in the work and rest regimen].

The authors report that a transition of a human organism to a non-standard work and rest regimen in conditions of hermetization is followed by the development of adaptation reactions of body protecting functions. The strength of these reactions is determined by the correspondence of the twenty-four-hour activity cyclogram to the circadian physiologic rhythm. The depression of protecting reactions, the slowing down of adaptation process and the appearance of disadaptation sings occur more often among operators, whose twenty-four-hour activity algorithm demands working from 04.00 to 12.00 and from 16.00 to 24.00 with a four-hour shift cycle. The correspondence of the work and rest regimen to the twenty-four-hour cycle of physiologic functions in the conditions of chronophysiologic tension, decreases adaptation changes and prevents the development of body protective and accommodative insufficiency.