Janosa A D, Zbinden A M, Feigenwinter P
Section of Research, University of Berne, Inselspital, Switzerland.
Acta Anaesthesiol Scand. 1994 Oct;38(7):672-8. doi: 10.1111/j.1399-6576.1994.tb03976.x.
A physical lung model for simulation of volatile anaesthetic uptake is described. Two communicating water-filled chambers simulate pulmonary mechanics allowing adjustment of functional residual capacity, resistance and compliance. The uptake of the volatile anaesthetics is reproduced by pumping gas from the lung chamber through a charcoal absorber at different rates; using a second pump for a bypass an arterial to end-tidal gradient can be generated. Changes of cardiac output are simulated by adjusting pump speed and of alveolar ventilation by adapting the ventilator setting. The results are reproducible and correspond with patient studies and computer stimulation, not necessitating empirical correction factors as in a previously described oil-based lung model. The model can serve as a teaching instrument, for the comparison and testing of anaesthetic equipment and the development of feedback systems.
本文描述了一种用于模拟挥发性麻醉剂摄取的物理肺模型。两个相互连通的充水腔室模拟肺力学，可调节功能残气量、阻力和顺应性。通过以不同速率将气体从肺腔室泵入活性炭吸收器来再现挥发性麻醉剂的摄取；使用第二个泵进行旁路可产生动脉血到呼气末的梯度。通过调节泵速来模拟心输出量的变化，通过调整呼吸机设置来模拟肺泡通气的变化。结果具有可重复性，与患者研究和计算机模拟相符，不像之前描述的油基肺模型那样需要经验校正因子。该模型可用作教学工具，用于麻醉设备的比较和测试以及反馈系统的开发。
