Alvarez J O
Department of International Health, University of Alabama at Birmingham 35294-0008.
Am J Clin Nutr. 1995 Feb;61(2):410S-416S. doi: 10.1093/ajcn/61.2.410S.
Many studies involving small animals have clearly shown that malnutrition affects tooth formation and causes increased dental caries. We have conducted two cross-sectional studies and one longitudinal study among Peruvian children to investigate the effect of early malnutrition on oral health. The cross-sectional studies have shown that in malnourished children the pattern of caries development as a function of age is significantly altered as a result of a delayed eruption and exfoliation of the deciduous teeth. This phenomenon has made difficult the observation by other scientists of a clear effect of nutritional status on total caries experience because the comparison of age-adjusted caries data between populations of children with different nutritional status is inappropriate. The use of peak caries activity has allowed the observation of a strong association between malnutrition and increased dental caries. The longitudinal study has confirmed the results of the cross-sectional studies and has demonstrated that one mild to moderate malnutrition episode occurring during the first year of life is associated with increased caries in both the deciduous and permanent teeth many years later.
许多涉及小动物的研究已清楚表明，营养不良会影响牙齿形成并导致龋齿增加。我们在秘鲁儿童中开展了两项横断面研究和一项纵向研究，以调查早期营养不良对口腔健康的影响。横断面研究表明，在营养不良的儿童中，由于乳牙萌出和脱落延迟，龋齿发展模式随年龄的变化显著改变。这一现象使得其他科学家难以观察到营养状况对总龋齿经历的明显影响，因为对不同营养状况儿童群体之间按年龄调整的龋齿数据进行比较并不合适。使用龋齿活动高峰期使得能够观察到营养不良与龋齿增加之间的紧密关联。纵向研究证实了横断面研究的结果，并表明在生命的第一年发生一次轻度至中度营养不良事件与多年后乳牙和恒牙龋齿增加有关。
