Aderaye G
Department of Internal Medicine, Faculty of Medicine, AddisAbaba University, Ethiopia.
West Afr J Med. 1994 Jul-Sep;13(3):142-5.
Over a two year period, we prospectively studied 110 adult patients with Community Acquired Pneumonia (CAP) who presented to the Black Lion Hospital, Addis Ababa, Ethiopia. Pneumococcal infection was diagnosed in 41% by the detection of pneumococcal antigen in sputum and other biologic fluids; in 72% by Gram stain of Lung Aspirate (LA) and in 67.5% by Gram stain of sputum. Blood and Lung Aspirate culture grew Streptococcus Pneumoniae in 4 cases (6%), Staphylococcus Aureus in 4 (6%), Enterobacteriacae in 3(5%), Pseudomonas, Klebsiella Pneumoniae and Strep. Viridans in one case each. Other non-bacterial causes included Mycoplasma Pneumoniae in 4 (4%) Influenza A in 4 (4%), Influenza B in 3 (3%) and Psittacosis/LGV in a 4 (4%). There was no case of Legionnaires disease. 39% had taken treatment before coming to hospital. The mortality was 11%. The study showed that antibiotic treatment during the preceding 36 hours did not affect the outcome of the Gram stain.
在两年的时间里，我们对110名成年社区获得性肺炎（CAP）患者进行了前瞻性研究，这些患者均前往埃塞俄比亚亚的斯亚贝巴的黑狮医院就诊。通过检测痰液和其他生物体液中的肺炎球菌抗原，41%的患者被诊断为肺炎球菌感染；通过肺穿刺抽吸物（LA）革兰氏染色，72%的患者被诊断为肺炎球菌感染；通过痰液革兰氏染色，67.5%的患者被诊断为肺炎球菌感染。血液和肺穿刺抽吸物培养中，4例（6%）培养出肺炎链球菌，4例（6%）培养出金黄色葡萄球菌，3例（5%）培养出肠杆菌科细菌，1例分别培养出铜绿假单胞菌、肺炎克雷伯菌和草绿色链球菌。其他非细菌性病因包括4例（4%）肺炎支原体、4例（4%）甲型流感、3例（3%）乙型流感和4例（4%）鹦鹉热/性病性淋巴肉芽肿。未发现军团病病例。39%的患者在入院前接受过治疗。死亡率为11%。该研究表明，在之前36小时内使用抗生素治疗并不影响革兰氏染色的结果。
