Aderaye G
Department of Internal Medicine, Faculty of Medicine, Addis Abeba University.
Ethiop Med J. 1994 Apr;32(2):115-23.
We prospectively studied 110 adult patients coming to Black Lion Hospital between August 1987 and July 1989 with community acquired pneumonia (CAP) for various etiologic agents and clinical and radiographic presentation. Streptococcus pneumoniae was the most common offending pathogen in 72% and 67.5% from sputum and lung aspirate (LA) Gram stain respectively, and in 41% by pneumococcal serotyping of sputum. Blood and LA culture grew Streptococcus pneumoniae in 4 (6%), Staphylococcus aureus in 4 (6%), Enterobacteriaceae in (3%), Pseudomonas, Klebsiella and Streptococcus viridans in one case each. Non-bacterial pathogens included Mycoplasma pneumoniae in 3 (3%), Influenza A in 4 (4%), Influenza B in 3 (3%) and psittacosis/LGV in 4 (4%). Fever, cough, chest pain, tachypnea and coarse crepitations/bronchial breathing were the most common presenting signs and symptoms. Thirty per cent had associated diarrhoea and vomiting initially and 9% had altered state of consciousness at admission. Six patients came in a state of shock. Thirty-nine per cent had underlying illnesses. Ninety-three per cent had either segmental or lobar consolidation. Parapneumonic effusion occurred in 14%. The mortality was 11%. Tachypnea, the presence of underlying illness, altered state of consciousness, extreme leucocytosis and the presence of bilateral and multilobar lung involvement were found to be signs of poor prognosis. Our finding is similar to those from other African countries, except that we are reporting psittacosis/LGV for the first time in Africa.
1987年8月至1989年7月期间,我们对110例因社区获得性肺炎(CAP)前来黑狮医院就诊的成年患者进行了前瞻性研究,以确定各种病原体及临床和影像学表现。肺炎链球菌是最常见的致病病原体,分别在72%的痰液和67.5%的肺穿刺液(LA)革兰氏染色中检出,在41%的痰液肺炎球菌血清分型中检出。血液和LA培养分别有4例(6%)培养出肺炎链球菌、4例(6%)培养出金黄色葡萄球菌、3例培养出肠杆菌科细菌,1例分别培养出铜绿假单胞菌、克雷伯菌和草绿色链球菌。非细菌性病原体包括3例(3%)肺炎支原体、4例(4%)甲型流感、3例(3%)乙型流感和4例(4%)鹦鹉热/性病性淋巴肉芽肿。发热、咳嗽、胸痛、呼吸急促和粗湿啰音/支气管呼吸音是最常见的症状和体征。30%的患者最初伴有腹泻和呕吐,9%的患者入院时意识状态改变。6例患者处于休克状态。39%的患者有基础疾病。93%的患者有节段性或大叶性实变。胸腔积液发生率为14%。死亡率为11%。呼吸急促、存在基础疾病、意识状态改变、极度白细胞增多以及双侧和多叶肺受累被发现是预后不良的迹象。我们的研究结果与其他非洲国家的研究结果相似,只是我们首次在非洲报告了鹦鹉热/性病性淋巴肉芽肿。