Roseeuw D, De Raeve L, Dangoisse C, Ramet J
Department of Dermatology, Academic Hospital, Vrije Universiteit, Brussel, Belgium.
Dermatology. 1994;189 Suppl 2:68-70. doi: 10.1159/000246998.
Junctional epidermolysis bullosa letalis type Herlitz Pearson is a genetically determined, life-threatening disease. Effective therapy has been lacking to date. Therefore any therapy that improves wound healing would be beneficial for these patients. Cultured epidermal grafts are known to enhance wound epithelialization and have been used with success in some epidermolysis bullosa disorders. Encouraged by these reports, we grafted cultured allogeneic keratinocytes to an infant with a junctional epidermolysis bullosa letalis type.
赫利茨·皮尔逊型致死性交界性大疱性表皮松解症是一种由基因决定的、危及生命的疾病。迄今为止，一直缺乏有效的治疗方法。因此，任何能改善伤口愈合的治疗方法对这些患者都将是有益的。已知培养的表皮移植物可促进伤口上皮形成，并已成功用于治疗某些大疱性表皮松解症。受这些报告的鼓舞，我们将培养的同种异体角质形成细胞移植到了一名患有致死性交界性大疱性表皮松解症的婴儿身上。
