Iai M, Tanabe Y, Goto M, Sugita K, Niimi H
Department of Pediatrics, Chiba University School of Medicine, Japan.
Acta Paediatr. 1994 Oct;83(10):1086-90. doi: 10.1111/j.1651-2227.1994.tb12991.x.
To determine the extent of brain damage in children with spastic diplegia, we analyzed the true midsagittal magnetic resonance imaging findings for the corpus callosum in 43 children with spastic diplegia and in 69 neurologically normal children. In the normal children, the thicknesses of the genu, midbody, splenium and the entire corpus callosum were found to increase with age, while the ratios of the thickness of the splenium and of the midbody to the length were constant, regardless of age. Both ratios were significantly reduced in diplegic children and the ratio for the splenium was highly correlated with the extent of motor impairment. Assessment of the morphometric changes in the corpus callosum using magnetic resonance imaging may contribute to the determination of the extent of brain damage in diplegic children.
为了确定痉挛性双侧瘫患儿的脑损伤程度，我们分析了43例痉挛性双侧瘫患儿和69例神经功能正常儿童的胼胝体真正矢状位磁共振成像结果。在正常儿童中，发现胼胝体膝部、体部、压部及整个胼胝体的厚度随年龄增长而增加，而压部和体部厚度与长度的比值则不随年龄变化而保持恒定。双侧瘫患儿的这两个比值均显著降低，且压部的比值与运动障碍程度高度相关。利用磁共振成像评估胼胝体的形态学变化可能有助于确定双侧瘫患儿的脑损伤程度。
