Leijser Lara M, Srinivasan Latha, Rutherford Mary A, Counsell Serena J, Allsop Joanna M, Cowan Frances M
Department of Paediatrics, Hammersmith Hospital, Imperial College, Du Cane Road, London W12 OHS, UK.
Pediatr Radiol. 2007 Jul;37(7):640-8. doi: 10.1007/s00247-007-0485-2. Epub 2007 May 8.
Structural size in the neonatal brain is of clinical importance. Cranial ultrasonography (cUS) is the primary method used for evaluating the neonatal brain and it is important to know whether linear measurements made using this technique are accurate.
To compare linear measurements of different cerebral structures made from neonatal cUS and contemporaneous MRI.
Preterm and term infants studies with cUS and MRI on the same day were studied. Linear measurements made using both techniques from many cerebral structures were compared using a paired t-test.
A total of 44 sets of scans from 26 preterm and 8 term infants were assessed. Small but significant differences between the cUS and MRI measurements (P<0.05) were found for the ventricular index, the posterior horn depth of the lateral ventricle, the extracerebral space and interhemispheric fissure, and the cortex of the cingulate gyrus. No significant differences were found for any other measurements.
Linear measurements from cUS are accurate for most neonatal cerebral structures. Significant differences compared to MRI were found for a few structures, but only for the cortex were the absolute differences marked and possibly of clinical importance.
新生儿脑结构大小具有临床重要性。头颅超声检查（cUS）是评估新生儿脑的主要方法，了解使用该技术进行的线性测量是否准确很重要。
比较新生儿cUS和同期MRI对不同脑结构的线性测量结果。
研究同日接受cUS和MRI检查的早产儿和足月儿。使用配对t检验比较两种技术对多种脑结构进行的线性测量结果。
共评估了26例早产儿和8例足月儿的44组扫描数据。发现cUS和MRI测量结果在脑室指数、侧脑室后角深度、脑外间隙和半球间裂以及扣带回皮质方面存在微小但显著的差异（P<0.05）。其他测量结果未发现显著差异。
cUS对大多数新生儿脑结构的线性测量是准确的。与MRI相比，少数结构存在显著差异，但只有皮质的绝对差异明显且可能具有临床重要性。
