Enhancement of 12-O-tetradecanoylphorbol-13-acetate-induced tumor necrosis factor alpha production by phenethylphthalimide analogs.
作者信息
Sasaki K, Shibata Y, Nishimura K, Hashimoto Y, Iwasaki S
机构信息
Institute of Molecular and Cellular Biosciences, University of Tokyo, Japan.
出版信息
Biol Pharm Bull. 1994 Sep;17(9):1313-5. doi: 10.1248/bpb.17.1313.
PMID:7841962
Abstract
Effects of phenyl-, benzyl-, phenethyl-, and phenylpropylphthalimides on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced tumor necrosis factor (TNF)-alpha production by human leukemia cell line HL-60 were examined. Among the four phthalimide derivatives, only phenethylphthalimide showed potent enhancing effect on TNF-alpha production.
摘要
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