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加拿大的大流行规划。

Pandemic planning in Canada.

作者信息

Tamblyn S E

机构信息

Perth District Health Unit, Stratford, Ontario, Canada.

出版信息

Eur J Epidemiol. 1994 Aug;10(4):503-5. doi: 10.1007/BF01719688.

Abstract

A Canadian plan for pandemic influenza was completed by the National Advisory Committee on Immunization in 1988. Its development took several years and involved consultation with provincial public health and laboratory authorities, the licensing body, manufacturers of influenza vaccine and antiviral agents, and representatives in the USA and UK. Key decisions in creating the pandemic plan include: (1) aiming for federal-provincial consensus on use of vaccine and antiviral drugs, (2) a selective vaccination approach (high-risk persons plus essential workers), (3) bulk purchasing and distribution of vaccine through the public sector, (4) leaving antiviral drugs on the open market, (5) careful planning of the communications strategy, and (6) increasing inter-pandemic use of flu vaccine in target groups. The plan addresses recognition of a pandemic; activation of a Pandemic Influenza Committee whose membership and responsibilities are spelled out; the federal-provincial decision making process; influenza vaccine considerations; amantadine and other antiviral agents; estimates of target group size, vaccine uptake, manufacturing capabilities and time frames; and communication considerations. Since 1988, influenza vaccine use has increased considerably in Canada and experience has been gained with amantadine. Manufacturing capability within Canada for influenza vaccine has also been enhanced. It is now time to update the plan, especially the targets, and to make sure that everyone involved remains aware of the assigned roles.

摘要

1988年,加拿大免疫咨询委员会完成了一项大流行性流感计划。该计划的制定历时数年,期间与省级公共卫生和实验室当局、许可机构、流感疫苗及抗病毒药物制造商以及美国和英国的代表进行了磋商。制定该大流行计划的关键决策包括:(1)力求在联邦和省级层面就疫苗和抗病毒药物的使用达成共识;(2)采取选择性接种方法(高危人群加关键岗位工作人员);(3)通过公共部门批量采购和分发疫苗;(4)将抗病毒药物投放开放市场;(5)精心规划沟通策略;(6)增加目标群体在大流行间期流感疫苗的接种量。该计划涉及对大流行的识别;启动一个明确成员构成和职责的大流行性流感委员会;联邦和省级的决策程序;流感疫苗的考量因素;金刚烷胺及其他抗病毒药物;目标群体规模、疫苗接种率、生产能力和时间框架的估算;以及沟通方面的考量因素。自1988年以来,加拿大流感疫苗的使用量大幅增加,并且积累了使用金刚烷胺的经验。加拿大国内流感疫苗的生产能力也有所提高。现在是时候更新该计划了,尤其是各项指标,并确保所有相关人员都清楚各自的指定职责。

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