Falcieri E, Gobbi P, Cataldi A, Zamai L, Faenza I, Vitale M
Istituto di Morfologia Umana Normale, Università di Chieti, Bologna.
Histochem J. 1994 Sep;26(9):754-63. doi: 10.1007/BF00158206.
During apoptosis, nuclear pores undergo strong modifications, which are described here in five different apoptotic models. Conventional electron microscopy, supported by freeze-fracture analysis, showed a constant migration of nuclear pores towards the diffuse chromatin areas. In contrast, dense chromatin areas appear pore-free and are frequently surrounded by strongly dilated cisternae. A possible functional significance of this pore behaviour during apoptosis is discussed.
在细胞凋亡过程中，核孔会发生显著变化，本文在五种不同的细胞凋亡模型中对此进行了描述。传统电子显微镜在冷冻断裂分析的支持下，显示核孔持续向弥散染色质区域迁移。相反，致密染色质区域似乎无孔，且常被高度扩张的池包围。本文讨论了细胞凋亡过程中这种孔行为可能的功能意义。
