Eberle L, Glück U
HNO-Klinik, Kantonsspital Luzern.
HNO. 1994 Nov;42(11):665-9.
Eighty-four patients with clinical findings of hyperactive rhinopathy and no significant septal deviations were treated for 4 weeks with topical applications of capsaicin, which is the pungent substance in hot peppers. A neutral solution of low-dose capsaicin allowed patients to administer self-therapy without the need for local anesthesia. The majority of the patients showed a marked reduction in symptoms without significant side effects. Patients with (additional) allergic or medication-related rhinopathy seemed to show fewer therapeutic effects when compared to patients with only hyperactive rhinopathy.
84例有鼻黏膜高反应性临床表现且无明显鼻中隔偏曲的患者，接受了为期4周的辣椒素局部治疗，辣椒素是辣椒中的辛辣物质。低剂量辣椒素的中性溶液使患者无需局部麻醉即可自行治疗。大多数患者症状明显减轻，且无明显副作用。与仅患有鼻黏膜高反应性的患者相比，患有（额外的）过敏性或药物相关性鼻病的患者似乎治疗效果较差。
