Arankalle V A, Tsarev S A, Chadha M S, Alling D W, Emerson S U, Banerjee K, Purcell R H
National Institute of Virology, Indian Council of Medical Research, Pune.
J Infect Dis. 1995 Feb;171(2):447-50. doi: 10.1093/infdis/171.2.447.
The age-specific seroprevalence of antibody to hepatitis A virus (HAV) and antibody to hepatitis E virus (HEV) were studied in persons in Pune, India, where both viruses are endemic. The data showed that HAV infected the majority of persons by age 3 years and virtually 100% by late childhood. In contrast, infection with HEV was rare in children and did not reach peak prevalence (33%-40%) until early adulthood. The reason for the differences in infection rates between HAV and HEV is not known. Age-specific antibody patterns in serum samples obtained 10 years apart show that neither HAV nor HEV has diminished in medical importance in this Indian community.
在印度浦那，甲型肝炎病毒（HAV）和戊型肝炎病毒（HEV）均为地方性流行，研究了这两种病毒抗体的年龄特异性血清流行率。数据显示，到3岁时，大多数人已感染HAV，到儿童晚期几乎100%的人已感染。相比之下，儿童感染HEV的情况很少见，直到成年早期才达到流行高峰（33%-40%）。HAV和HEV感染率存在差异的原因尚不清楚。相隔10年采集的血清样本中的年龄特异性抗体模式表明，在这个印度社区，HAV和HEV的医学重要性均未减弱。
