Mishra R N, Kanungo M S
Department of Zoology, Banaras Hindu University, Varanasi, India.
Mol Biol Rep. 1994 Jul;20(1):15-8. doi: 10.1007/BF00999850.
Age-related changes occur in histones of the liver and oviduct of the female quail. In the liver an extra histone band, named HCX, between H2A and H4, is observed that increases with age. In the oviduct, a large complex of histones is seen which is tissue-specific. This complex declines with increasing age. The changes in the histones of the oviduct of adult and old birds in response to estradiol and progesterone are age-related. In the adult, the histone-complex increases after administration of either one of the hormones. In old birds, however, it is seen only after progesterone administration. Thus, the alterations in histones in the birds are not only tissue- and age-related, but also vary in response to steroid hormones.
雌性鹌鹑肝脏和输卵管中的组蛋白会发生与年龄相关的变化。在肝脏中，观察到在H2A和H4之间有一条额外的组蛋白带，名为HCX，其会随着年龄增长而增加。在输卵管中，可见一个大型的组蛋白复合体，它具有组织特异性。该复合体随着年龄的增加而减少。成年和老龄鸟类输卵管中的组蛋白对雌二醇和孕酮的反应变化与年龄相关。在成年鸟类中，给予任何一种激素后组蛋白复合体都会增加。然而，在老龄鸟类中，只有在给予孕酮后才会出现这种情况。因此，鸟类组蛋白的变化不仅与组织和年龄有关，而且对类固醇激素的反应也有所不同。
