Differentiation and cancer: the conditional autonomy of phenotype.
作者信息
Lynch R G
机构信息
Department of Pathology, University of Iowa College of Medicine, Iowa City 52242.
出版信息
Proc Natl Acad Sci U S A. 1995 Jan 31;92(3):647-8. doi: 10.1073/pnas.92.3.647.
Abstract
摘要
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Proc Natl Acad Sci U S A. 1995 Jan 31;92(3):647-8. doi: 10.1073/pnas.92.3.647.
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The bone marrow of multiple myeloma patients contains B cell populations at different stages of differentiation that are clonally related to the malignant plasma cell.多发性骨髓瘤患者的骨髓中含有处于不同分化阶段的B细胞群体，这些群体与恶性浆细胞存在克隆相关性。
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Suppressor T cell action inhibits the expression of an excluded immunoglobulin gene.抑制性T细胞的作用会抑制一个被排除的免疫球蛋白基因的表达。
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