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1
Differentiation and cancer: the conditional autonomy of phenotype.分化与癌症：表型的条件自主性
Proc Natl Acad Sci U S A. 1995 Jan 31;92(3):647-8. doi: 10.1073/pnas.92.3.647.
2
[Effects of cell differentiation on the induction and inhibition of cancers].[细胞分化对癌症诱导和抑制的影响]
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Transdifferentiation of neoplastic cells.
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Retrodifferentiation and the fetal patterns of gene expression in cancer.癌症中的逆向分化与基因表达的胎儿模式
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Deletion of essential functions and tumorigenesis.基本功能的缺失与肿瘤发生
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The genesis of tumours--mutation or abnormal differentiation?肿瘤的起源——是突变还是异常分化？
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[Studies of growth, differentiation and neoplastic transformation of human and animal cells--views and trends:1985-1988].[人和动物细胞的生长、分化及肿瘤转化研究——观点与趋势：1985 - 1988年]
Postepy Biochem. 1988;34(4):269-71.
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[Plasticity of the cellular phenotype].[细胞表型的可塑性]
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引用本文的文献

1
Loss of GATA4 and GATA6 expression specifies ovarian cancer histological subtypes and precedes neoplastic transformation of ovarian surface epithelia.GATA4和GATA6表达缺失可明确卵巢癌的组织学亚型，并先于卵巢表面上皮的肿瘤转化。
PLoS One. 2009 Jul 31;4(7):e6454. doi: 10.1371/journal.pone.0006454.
2
Differentiation and cancer in the mammary gland: shedding light on an old dichotomy.乳腺中的分化与癌症：揭示一种古老的二分法。
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3
Role of intermediate filaments in migration, invasion and metastasis.中间丝在迁移、侵袭和转移中的作用。
Cancer Metastasis Rev. 1996 Dec;15(4):507-25. doi: 10.1007/BF00054016.
4
Experimental co-expression of vimentin and keratin intermediate filaments in human breast cancer cells results in phenotypic interconversion and increased invasive behavior.波形蛋白和角蛋白中间丝在人乳腺癌细胞中的实验性共表达导致表型相互转化和侵袭行为增加。
Am J Pathol. 1997 Feb;150(2):483-95.

本文引用的文献

1
Evidence for a bone marrow B cell transcribing malignant plasma cell VDJ joined to C mu sequence in immunoglobulin (IgG)- and IgA-secreting multiple myelomas.在分泌免疫球蛋白（IgG）和IgA的多发性骨髓瘤中，存在骨髓B细胞转录恶性浆细胞VDJ与免疫球蛋白重链恒定区（Cμ）序列连接的证据。
J Exp Med. 1993 Sep 1;178(3):1091-6. doi: 10.1084/jem.178.3.1091.
2
The bone marrow of multiple myeloma patients contains B cell populations at different stages of differentiation that are clonally related to the malignant plasma cell.多发性骨髓瘤患者的骨髓中含有处于不同分化阶段的B细胞群体，这些群体与恶性浆细胞存在克隆相关性。
J Exp Med. 1993 Sep 1;178(3):1023-31. doi: 10.1084/jem.178.3.1023.
3
T cells induce terminal differentiation of transformed B cells to mature plasma cell tumors.T细胞诱导转化的B细胞终末分化为成熟浆细胞瘤。
Proc Natl Acad Sci U S A. 1995 Jan 31;92(3):649-53. doi: 10.1073/pnas.92.3.649.
4
Cytogenetic evidence for the clonal nature of Richter's syndrome.里氏综合征克隆性质的细胞遗传学证据。
Blood. 1981 Jul;58(1):183-6.
5
Richter's syndrome in chronic lymphocytic leukemia.慢性淋巴细胞白血病中的里氏综合征。
Cancer. 1980 Jul 1;46(1):118-34. doi: 10.1002/1097-0142(19800701)46:1<118::aid-cncr2820460120>3.0.co;2-j.
6
Immunoregulation of murine myeloma in vitro. II. Suppression of MOPC-315 immunoglobulin secretion and synthesis by idiotype-specific suppressor T cells.小鼠骨髓瘤的体外免疫调节。II. 独特型特异性抑制性T细胞对MOPC - 315免疫球蛋白分泌和合成的抑制作用
J Exp Med. 1982 Mar 1;155(3):852-62. doi: 10.1084/jem.155.3.852.
7
Suppressor T cell action inhibits the expression of an excluded immunoglobulin gene.抑制性T细胞的作用会抑制一个被排除的免疫球蛋白基因的表达。
Science. 1983 Jun 24;220(4604):1389-91. doi: 10.1126/science.6222474.
8
Maturation of tumors of the sympathetic nervous system. Report of long-term survival in 2 patients, one with disseminated osseous metastases, and review of cases from the literature.交感神经系统肿瘤的成熟。2例长期存活报告，其中1例有弥漫性骨转移，并复习文献中的病例。
Cancer. 1965 Nov;18(11):1510-6. doi: 10.1002/1097-0142(196511)18:11<1510::aid-cncr2820181124>3.0.co;2-h.
9
Delineation of a novel pre-B cell component in plasma cell myeloma: immunochemical, immunophenotypic, genotypic, cytologic, cell culture, and kinetic features.浆细胞骨髓瘤中一种新型前B细胞成分的描绘：免疫化学、免疫表型、基因型、细胞学、细胞培养及动力学特征
Blood. 1987 Oct;70(4):932-42.
10
Detection of monoclonal B lymphocytes in bone marrow and peripheral blood of multiple myeloma patients by immunoglobulin gene rearrangement studies.
Br J Haematol. 1989 Nov;73(3):289-95. doi: 10.1111/j.1365-2141.1989.tb07742.x.

Differentiation and cancer: the conditional autonomy of phenotype.

作者信息

Lynch R G

机构信息

Department of Pathology, University of Iowa College of Medicine, Iowa City 52242.

出版信息

Proc Natl Acad Sci U S A. 1995 Jan 31;92(3):647-8. doi: 10.1073/pnas.92.3.647.

DOI:10.1073/pnas.92.3.647
PMID:7846030
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC42676/
Abstract
摘要