Piepgras A, Gückel F, Lämmler B, Weigel R, Schmiedek P
Neurochirurgische Klinik, Klinikum Mannheim, Klinische Fakultät Mannheim, Universität Heidelberg.
Radiologe. 1994 Nov;34(11):627-31.
We describe the non-invasive assessment of cerebrovascular reserve capacity by means of near-infrared spectroscopy (NIRS) and magnetic resonance imaging. Both methods are compared with transcranial Doppler sonography. There is a good correlation of the three methods in the changes in cerebral oxygen saturation and in blood velocity following acetazolamide stimulation of cerebral blood flow, except found in one patient with unilateral carotid artery occlusion. In this patient we found a decreased cerebrovascular reserve capacity, revealed by a magnetic resonance technique designed to quantify CBV and CBF. We postulate a raised oxygen extraction as the cause of his changes in oxygen saturation.
我们描述了通过近红外光谱法（NIRS）和磁共振成像对脑血管储备能力进行的无创评估。将这两种方法与经颅多普勒超声检查进行了比较。除了一名单侧颈动脉闭塞的患者外，三种方法在乙酰唑胺刺激脑血流后脑氧饱和度变化和血流速度变化方面具有良好的相关性。在该患者中，我们发现通过一种旨在量化脑血容量（CBV）和脑血流量（CBF）的磁共振技术显示其脑血管储备能力下降。我们推测氧摄取增加是其氧饱和度变化的原因。
