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[1971年至1990年哈雷/萨勒大学妇科诊所复发性外阴癌——诊断与治疗结果]

[Recurrent vulvar carcinoma at the Halle/S. University Gynecologic Clinic 1971-1990--diagnosis and results of therapy].

作者信息

Strauss H G, Lampe D

机构信息

Klinik und Poliklinik für Gynäkologie, Martin-Luther-Universität Halle-Wittenberg.

出版信息

Zentralbl Gynakol. 1994;116(12):675-8.

PMID:7846979
Abstract

We analysed the recurrences of vulvar carcinoma diagnosed at the Gynecological University Hospital of Halle/S. between 1971 and 1990. 37 cases were evaluated. 75.7% of all patients had a local recurrence of the vulvar region; no distant site of recurrent tumour outside the pelvis was described. Only 48.6% of the recurrences occurred within a period of two years after primary therapy. The five year survival after diagnosis of recurrent disease was 56%. The influence of potential prognostic factors on survival was evaluated by a multivariate analysis according to the Cox model. Only the localisation of recurrence represented a statistically significant prognostic factor. Patients with a local recurrent carcinoma had a significant survival advantage as compared to those cases with inguinal or pelvic node tumour (p = 0.0021).

摘要

我们分析了1971年至1990年间在哈雷/萨勒妇科大学医院诊断出的外阴癌复发情况。评估了37例病例。所有患者中有75.7%出现外阴区域局部复发;未描述盆腔外远处复发病灶。仅48.6%的复发发生在初次治疗后的两年内。复发性疾病诊断后的五年生存率为56%。根据Cox模型通过多变量分析评估潜在预后因素对生存的影响。只有复发部位是具有统计学意义的预后因素。与腹股沟或盆腔淋巴结肿瘤患者相比,局部复发性癌患者具有显著的生存优势(p = 0.0021)。

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