Wetterling T, Kanitz R D, Veltrup C, Driessen M
Department of Psychiatry, University Medical School of Luebeck, Federal Republic of Germany.
Alcohol Clin Exp Res. 1994 Oct;18(5):1100-2. doi: 10.1111/j.1530-0277.1994.tb00087.x.
Up to now, clinical predictors for the course of the alcohol withdrawal syndrome, especially for the occurrence of a delirium, are lacking. Thus, this study was undertaken to examine whether clinical routine investigations at admission before the withdrawal syndrome can reveal factors indicating a higher risk for the development of a delirium. Our results showed that decreased serum electrolyte concentrations (i.e., chloride and potassium), elevated ALT, and gamma-glutamyltransferase serum levels, as well as ataxia and polyneuropathy at the neurological examination, indicate a higher risk for the development of an alcohol withdrawal delirium.
到目前为止，缺乏针对酒精戒断综合征病程，尤其是谵妄发生的临床预测指标。因此，开展本研究以检验在戒断综合征出现之前入院时的临床常规检查能否揭示表明谵妄发生风险较高的因素。我们的结果显示，血清电解质浓度降低（即氯和钾）、谷丙转氨酶升高以及γ-谷氨酰转移酶血清水平升高，还有神经学检查时出现共济失调和多发性神经病，均表明发生酒精戒断谵妄的风险较高。
