Ermilov V V, Serov V V
Arkh Patol. 1994 Jul-Aug;56(4):9-14.
New data, concerning incidence, morphology, clinical manifestations of eye amyloidosis are obtained following its study using modern verification methods. Eye amyloidosis is represented either by its local forms or is associated with a generalized amyloidosis. Local eye amyloidosis predominated and may be isolated and combined. Isolated amyloidosis is represented by two variants: with an involvement of the anterior part of the eye in the form of pseudoexfoliative amyloidosis (PEA) and involvement of the posterior part of the eye with the development of senile macular degeneration (SMD). Local amyloidosis may be associated with senile cerebral amyloidosis, insular amyloidosis of pancreas and both. Predominant involvement of the eye vessels and extraocular structures is an important feature of the ocular amyloidosis as a manifestation of generalized forms. Vitreous body is involved mainly in FAP. New clinico-morpho-pathogenetic classification is suggested.
采用现代验证方法对眼淀粉样变性进行研究后，获得了有关其发病率、形态学及临床表现的新数据。眼淀粉样变性表现为局部形式或与全身性淀粉样变性相关。局部眼淀粉样变性占主导，可分为孤立性和合并性。孤立性淀粉样变性有两种类型：一种是以假性剥脱性淀粉样变性（PEA）形式累及眼前部，另一种是随着老年性黄斑变性（SMD）的发展累及眼后部。局部淀粉样变性可能与老年性脑淀粉样变性、胰腺岛状淀粉样变性或两者均有关。眼部血管和眼外结构的主要受累是作为全身性形式表现的眼淀粉样变性的一个重要特征。玻璃体主要在家族性淀粉样多神经病（FAP）中受累。提出了新的临床形态学发病机制分类。
