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眼淀粉样变性合并其他老年病理改变

[Amyloidosis of the eye combined with other senile pathology].

作者信息

Ermilov V V

出版信息

Arkh Patol. 1993;55(6):43-5.

PMID:8122975
Abstract

478 eyes of 313 patients aged from 25 to 90 years and older were investigated (postmortem and surgical material was used). Patients had cataracts, glaucoma, diabetes mellitus. The goal of the study was establishing the amyloid nature of the pseudoexfoliative material (PEM) in the anterior part of the eye. The study showed PEM to be a variety of the amyloid-pseudoexfoliative amyloid (PEA) which was found in 66 (14%) eyes. The localisation and morphology of PEA in various parts of the eye are described in detail. PEA may be the only manifestation of the senile eye amyloidosis, but may be combined with insular amyloidosis of the pancreas.

摘要

对313例年龄在25岁至90岁及以上患者的478只眼睛进行了研究(使用了尸检和手术材料)。患者患有白内障、青光眼、糖尿病。本研究的目的是确定眼前部假性剥脱物质(PEM)的淀粉样变性性质。研究表明,PEM是淀粉样假性剥脱性淀粉样蛋白(PEA)的一种变体,在66只(14%)眼睛中被发现。详细描述了PEA在眼睛各个部位的定位和形态。PEA可能是老年眼淀粉样变性的唯一表现,但也可能与胰腺岛状淀粉样变性合并存在。

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