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特发性颅内高压。缺乏脑水肿的组织学证据。

Idiopathic intracranial hypertension. Lack of histologic evidence for cerebral edema.

作者信息

Wall M, Dollar J D, Sadun A A, Kardon R

机构信息

Department of Neurology, University of Iowa, College of Medicine, Iowa City.

出版信息

Arch Neurol. 1995 Feb;52(2):141-5. doi: 10.1001/archneur.1995.00540260045014.

DOI:10.1001/archneur.1995.00540260045014
PMID:7848121
Abstract

OBJECTIVE

To study brain histologic features in two cases of idiopathic intracranial hypertension (pseudotumor cerebri) at autopsy.

DESIGN

Formaldehyde solution-fixed sections of cerebral white matter in two cases and structures of the sensory visual system in one case were analyzed.

SETTING

University medical center.

PATIENTS

Two patients with idiopathic intracranial hypertension who died unexpectedly.

MAIN OUTCOME MEASURE

Histologic study of cerebral white matter in the two patients.

RESULTS

We did not find histologic evidence of any type of cerebral edema in our patients. Review of a portion of the material from a previous report is also consistent with this conclusion.

CONCLUSION

If patients with idiopathic intracranial hypertension have histologically apparent cerebral edema, it is not a consistent finding.

摘要

目的

研究两例特发性颅内高压(假性脑瘤)尸检时的脑组织学特征。

设计

分析两例脑白质经甲醛溶液固定的切片以及一例感觉视觉系统的结构。

单位

大学医学中心。

患者

两名意外死亡的特发性颅内高压患者。

主要观察指标

对两名患者的脑白质进行组织学研究。

结果

我们在患者中未发现任何类型脑水肿的组织学证据。对先前一份报告中的部分材料进行回顾也与此结论一致。

结论

如果特发性颅内高压患者存在组织学上明显的脑水肿,这并非是一个一致的发现。

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Idiopathic intracranial hypertension. Lack of histologic evidence for cerebral edema.特发性颅内高压。缺乏脑水肿的组织学证据。
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