Müller-Brand J, Staub J J, Moeglen C, Peyer P
Nuklearmedizin. 1978 Apr;17(2):70-3.
A comparative study of thyroid uptake and PB131I in two groups of 20 euthyroid persons each was performed. In one group 131I was administered in the form of capsules and in the other as a solution. The application of 131I in capsule form showed no significant decrease of thyroid uptake at 2, 24 and 48 hr but a significant diminishment of PB131I 48 hr after capsule ingestion (p less than 0,05). In 3 patients the scintiscans of the abdomen 24 hr after administration of three 131I capsules (90 muCi) revealed no circumscribed areas of activity. Because the iodine metabolism is dependent upon the kind of carrier, we conclude that for thyroid uptake measurements and the following 131I therapy the same 131I preparation should be used.
对两组各20名甲状腺功能正常的人进行了甲状腺摄取和PB131I的比较研究。一组口服131I胶囊，另一组口服131I溶液。口服胶囊形式的131I在2、24和48小时时甲状腺摄取无显著下降，但在摄入胶囊48小时后PB131I显著减少（p<0.05）。3例患者在服用3粒131I胶囊（90μCi）24小时后腹部闪烁扫描未发现局限性活性区域。由于碘代谢取决于载体类型，我们得出结论，对于甲状腺摄取测量和后续的131I治疗，应使用相同的131I制剂。
