• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Phase II study of gemcitabine (2',2'-difluorodeoxycytidine) given as a twice weekly schedule to previously untreated patients with non-small cell lung cancer.

作者信息

Lund B, Ryberg M, Petersen P M, Anderson H, Thatcher N, Dombernowsky P

机构信息

Department of Oncology, Rigshospitalet, Denmark.

出版信息

Ann Oncol. 1994 Nov;5(9):852-3. doi: 10.1093/oxfordjournals.annonc.a059018.

DOI:10.1093/oxfordjournals.annonc.a059018
PMID:7848889
Abstract
摘要

相似文献

1
Phase II study of gemcitabine (2',2'-difluorodeoxycytidine) given as a twice weekly schedule to previously untreated patients with non-small cell lung cancer.吉西他滨(2',2'-二氟脱氧胞苷)每周两次给药用于既往未接受过治疗的非小细胞肺癌患者的II期研究。
Ann Oncol. 1994 Nov;5(9):852-3. doi: 10.1093/oxfordjournals.annonc.a059018.
2
Activity of gemcitabine in non-small-cell lung cancer: results of the Japan gemcitabine group (A) phase II study.吉西他滨治疗非小细胞肺癌的活性:日本吉西他滨组(A)II期研究结果
Cancer Chemother Pharmacol. 1998;41(3):217-22. doi: 10.1007/s002800050731.
3
A randomized study comparing two different schedules of administration of cisplatin in combination with gemcitabine in advanced nonsmall cell lung carcinoma.一项比较顺铂与吉西他滨联合应用于晚期非小细胞肺癌的两种不同给药方案的随机研究。
Cancer. 2000 Oct 15;89(8):1714-9. doi: 10.1002/1097-0142(20001015)89:8<1714::aid-cncr10>3.0.co;2-7.
4
Gemcitabine as single agent chemotherapy in elderly patients with stages III-IV non-small cell lung cancer (NSCLC): a phase II study.吉西他滨单药化疗用于老年Ⅲ-Ⅳ期非小细胞肺癌(NSCLC)患者:一项Ⅱ期研究。
Anticancer Res. 2002 Sep-Oct;22(5):3053-6.
5
Phase II study of gemcitabine and vindesine in patients with previously untreated non-resectable non-small-cell lung cancer.吉西他滨与长春地辛用于既往未治疗的不可切除非小细胞肺癌患者的II期研究。
Br J Cancer. 1999 Feb;79(5-6):875-81. doi: 10.1038/sj.bjc.6690140.
6
Paclitaxel and gemcitabine combination in a biweekly schedule in patients with advanced non small-cell lung cancer: a phase I study.紫杉醇与吉西他滨联合每两周给药方案用于晚期非小细胞肺癌患者的I期研究
Cancer Chemother Pharmacol. 2005 Dec;56(6):653-8. doi: 10.1007/s00280-005-1009-0. Epub 2005 Jun 4.
7
Phase II trial of gemcitabine in advanced non-small-cell lung cancer.吉西他滨用于晚期非小细胞肺癌的II期试验。
Wien Klin Wochenschr. 1997 Sep 19;109(17):688-91.
8
Gemcitabine and vincristine: an effective outpatient regimen with low myelotoxicity for stage IV non-small cell lung cancer.吉西他滨与长春新碱:一种对IV期非小细胞肺癌有效的、骨髓毒性低的门诊治疗方案。
Neoplasma. 2001;48(3):200-2.
9
A randomized phase II trial evaluating standard (50 mg/min) versus low (10 mg/min) infusion duration of gemcitabine as first-line treatment in advanced non-small-cell lung cancer patients who are not eligible for platinum-based chemotherapy.一项随机II期试验,评估吉西他滨标准输注持续时间(50毫克/分钟)与低输注持续时间(10毫克/分钟)作为一线治疗方案,用于不适合铂类化疗的晚期非小细胞肺癌患者。
Lung Cancer. 2006 Jun;52(3):319-25. doi: 10.1016/j.lungcan.2006.03.004. Epub 2006 Apr 19.
10
First line chemotherapy with gemcitabine in advanced non-small cell lung cancer elderly patients: a randomized phase II study of 3-week versus 4-week schedule.吉西他滨用于老年晚期非小细胞肺癌患者的一线化疗:3周与4周方案的随机II期研究
Lung Cancer. 2005 Mar;47(3):405-12. doi: 10.1016/j.lungcan.2004.08.012.

引用本文的文献

1
Phase I trial of radiotherapy concurrent with twice-weekly gemcitabine for head and neck cancer: translation from preclinical investigations aiming to improve the therapeutic ratio.头颈部癌症同期放疗联合每周两次吉西他滨治疗的 I 期临床试验:从旨在提高治疗比率的临床前研究转化而来。
Transl Oncol. 2014 Aug;7(4):479-83. doi: 10.1016/j.tranon.2014.04.016.
2
Phase I and pharmacokinetic study of 3'-C-ethynylcytidine (TAS-106), an inhibitor of RNA polymerase I, II and III,in patients with advanced solid malignancies.I 期和药代动力学研究 3'-C-乙炔基胞苷(TAS-106),一种 RNA 聚合酶 I、II 和 III 的抑制剂,在晚期实体恶性肿瘤患者中的应用。
Invest New Drugs. 2012 Feb;30(1):316-26. doi: 10.1007/s10637-010-9535-y. Epub 2010 Sep 14.
3
Comparison of pharmacokinetics, efficacy and toxicity profile of gemcitabine using two different administration regimens in Chinese patients with non-small-cell lung cancer.
在中国非小细胞肺癌患者中使用两种不同给药方案对吉西他滨的药代动力学、疗效和毒性特征进行比较。
J Zhejiang Univ Sci B. 2007 May;8(5):307-13. doi: 10.1631/jzus.2007.B0307.
4
Pharmacokinetics of gemcitabine in Chinese patients with non-small-cell lung cancer.吉西他滨在中国非小细胞肺癌患者中的药代动力学
J Zhejiang Univ Sci B. 2005 May;6(5):446-50. doi: 10.1631/jzus.2005.B0446.
5
Gemcitabine twice weekly as a radiosensitiser for the treatment of brain metastases in patients with carcinoma: a phase I study.吉西他滨每周两次作为放射增敏剂用于治疗癌性脑转移患者:一项I期研究。
Br J Cancer. 2005 Mar 14;92(5):815-9. doi: 10.1038/sj.bjc.6602444.
6
Cancer and leukemia group B (CALGB) 89805: phase II chemoradiation trial using gemcitabine in patients with locoregional adenocarcinoma of the pancreas.癌症与白血病B组(CALGB)89805研究:一项使用吉西他滨对局部区域胰腺癌患者进行的II期放化疗试验。
Int J Gastrointest Cancer. 2003;34(2-3):107-16. doi: 10.1385/ijgc:34:2-3:107.
7
A Bayesian re-assessment of two Phase II trials of gemcitabine in metastatic nasopharyngeal cancer.吉西他滨用于转移性鼻咽癌的两项II期试验的贝叶斯重新评估。
Br J Cancer. 2002 Mar 18;86(6):843-50. doi: 10.1038/sj.bjc.6600199.
8
Gemcitabine in non-small cell lung cancer (NSCLC).吉西他滨用于非小细胞肺癌(NSCLC)。
Invest New Drugs. 2000 Feb;18(1):29-42. doi: 10.1023/a:1006327729228.
9
Phase I study of gemcitabine using a once every 2 weeks schedule.吉西他滨每两周一次给药方案的I期研究。
Br J Cancer. 1997;76(11):1489-93. doi: 10.1038/bjc.1997.583.
10
Gemcitabine. A review of its pharmacology and clinical potential in non-small cell lung cancer and pancreatic cancer.吉西他滨。对其在非小细胞肺癌和胰腺癌中的药理学及临床应用潜力的综述。
Drugs. 1997 Sep;54(3):447-72. doi: 10.2165/00003495-199754030-00009.