Abraham K, Hille A, Ende M, Helge H
Kinderklinik der FU Berlin (Kaiserin Auguste Victoria Haus), Germany.
Chemosphere. 1994 Nov-Dec;29(9-11):2279-86. doi: 10.1016/0045-6535(94)90395-6.
Intake and fecal excretion of PCDDs, PCDFs, HCB and PCBs (IUPAC Nos. 138, 153, 180) were measured in a breast-fed and a formula-fed infant at the age of 1 and 5 months. As expected, the intake of these compounds was clearly higher in the breast-fed infant. In this baby an almost complete absorption was observed for lower chlorinated PCDDs and PCDFs and also for HCB and PCBs, whereas for hepta- and octachlorinated PCDDs and PCDFs fecal excretion was considerably higher (from 20% up to nearly 100% of the intake). Due to low concentrations in diet and feces of the formula-fed infant an evaluation was possible only for a few compounds at the age of 5 months. These values were in the same range when compared with those of the breast-fed infant. For collection of feces new cotton diapers were used which were pre-extracted in order to reduce the levels of polychlorinated compounds. Unexpectedly, after washing the tissue a much higher contamination was observed which made a calculation of fecal excretion rates in the formula-fed infant at the age of 1 month impossible.
对一名母乳喂养婴儿和一名配方奶喂养婴儿在1个月和5个月大时的多氯二苯并对二噁英（PCDDs）、多氯二苯并呋喃（PCDFs）、六氯苯（HCB）和多氯联苯（IUPAC编号138、153、180）的摄入量和粪便排泄量进行了测量。正如预期的那样，母乳喂养婴儿中这些化合物的摄入量明显更高。在这名婴儿中，观察到低氯代PCDDs和PCDFs以及HCB和PCBs几乎完全被吸收，而对于七氯和八氯代PCDDs和PCDFs，粪便排泄量则要高得多（占摄入量的20%至近100%）。由于配方奶喂养婴儿的饮食和粪便中浓度较低，仅在5个月大时对少数化合物进行了评估。与母乳喂养婴儿的值相比，这些值处于相同范围。为了收集粪便，使用了预先提取过的新棉质尿布，以降低多氯化合物的含量。出乎意料的是，清洗尿布后观察到污染程度更高，这使得无法计算1个月大的配方奶喂养婴儿的粪便排泄率。
