局部应用前列腺素对人体鼻通气的影响。
Effect of topical prostaglandins on nasal patency in man.
作者信息
Karim S M, Adaikan P G, Kunaratnam N
出版信息
Prostaglandins. 1978 Mar;15(3):457-62. doi: 10.1016/0090-6980(78)90129-6.
The effect of prostaglandin E1 and 17 phenyl trinor PGE2 on nasal patency has been studied in healthy volunteers and in patients with vasomotor and allergic rhinitis. Both drugs applied topically increased nasal patency. The effect of a single dose of either compound lasted for several hours. Prostaglandin E1 produced nasal irritation and throbbing, lacrimation, headache and sore throat. Except for occasional brief nasal irritation, these side effects were not encountered with 17 phenyl trinor PGE2.
在健康志愿者以及患有血管运动性鼻炎和过敏性鼻炎的患者中，研究了前列腺素E1和17-苯基-13,14-二降前列腺素E2对鼻通畅度的影响。两种药物局部应用均能提高鼻通畅度。单次给药后，两种化合物的作用均可持续数小时。前列腺素E1会引起鼻刺激、搏动、流泪、头痛和喉咙痛。除偶尔出现短暂的鼻刺激外，17-苯基-13,14-二降前列腺素E2未出现这些副作用。
Zotero 插件