17-苯基前列腺素F2α对人体鼻通畅度的影响。
Effect of 17 phenyl PGF2 alpha on nasal patency in man.
作者信息
Karim S M, Adaikan P G, Kunaratnam N
出版信息
Prostaglandins Med. 1979 Jul;3(1):33-7. doi: 10.1016/0161-4630(79)90013-2.
PMID:95330
Abstract
The effect of three different doses (12.5 microgram, 25 microgram and 50 microgram) of 17 phenyl PGF2 alpha on nasal patency in fourteen patients with vasomotor rhinitis was studied on separate occasions. In all subjects the three doses of the prostaglandin analogue increased nasal patency for varying duration. With the 50 microgram single dose the duration of action ranged between three hours and more than seven hours. There were no side effects in most of the patients.
摘要
研究了三种不同剂量（12.5微克、25微克和50微克）的17-苯基前列腺素F2α对14例血管运动性鼻炎患者鼻通畅度的影响，研究在不同时间进行。在所有受试者中，这三种剂量的前列腺素类似物均在不同时间段内增加了鼻通畅度。单次给予50微克剂量时，作用持续时间在3小时至7小时以上。大多数患者未出现副作用。
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