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混合性结缔组织病:复发性视神经病变和横贯性脊髓病。血浆置换治疗成功。

Mixed connective tissue disease: recurrent episodes of optic neuropathy and transverse myelopathy. Successful treatment with plasmapheresis.

作者信息

Flechtner K M, Baum K

机构信息

Universitätsklinikum Rudolf Virchow, Freie Universität Berlin, Germany.

出版信息

J Neurol Sci. 1994 Nov;126(2):146-8. doi: 10.1016/0022-510x(94)90264-x.

DOI:10.1016/0022-510x(94)90264-x
PMID:7853019
Abstract

Severe neuropsychiatric manifestations in mixed connective tissue disease (MCTD) are thought to be quite rare. We report an unusual case of MCTD with recurrent optic neuropathy and transverse myelopathy suggestive of a relapsing-remitting demyelinating disorder. Symptoms responded dramatically to a treatment with plasmapheresis and immunosuppressive medication.

摘要

混合性结缔组织病(MCTD)中的严重神经精神表现被认为相当罕见。我们报告了一例不寻常的MCTD病例,该病例反复出现视神经病变和横贯性脊髓病,提示为复发缓解型脱髓鞘疾病。症状对血浆置换和免疫抑制药物治疗反应显著。

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Lower In-Hospital Mortality with Plasma Exchange than Plasmapheresis in a Subgroup Analysis of 374 Lupus Patients.
374 例狼疮患者亚组分析显示,血浆置换的住院死亡率低于血浆分离。
Biomed Res Int. 2018 May 2;2018:9707932. doi: 10.1155/2018/9707932. eCollection 2018.
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Role of low plasma volume treatment on clinical efficacy of plasmapheresis in neuromyelitis optica.低血浆容量治疗在视神经脊髓炎血浆置换临床疗效中的作用
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Transverse myelitis.横贯性脊髓炎。
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