Szmidt M, Gondorowicz K
Kliniki Pneumonologii i Alergologii IMW AM, Lodzi.
Pol Tyg Lek. 1994;49(14-15):343-4.
A 42-year-old man reported attacks of dyspnoea on non-professional exposure to ash wood dust. The skin prick tests with common allergens and ash pollen were positive. Inhalation of ash wood dust (challenge test) elicited a very strong, immediate bronchospastic reaction, associated with profuse watery rhinorrhea, conjunctival congestion and lacrimation. The symptoms did not occurred after inhalation of pine wood dust. A positive skin (prick test) reaction to ash wood extract was documented. When the patient remained unexposed to ash wood dust the dyspnoea subsided and 4-fold decrease in bronchial reactivity to histamine-PC20 increase from 0.53 mg/ml to 2.1 mg/ml (according to Cockroft) was observed. The authors conclude that the immediate bronchial reaction to inhaled ash wood dust and the immediate skin positive response to ash wood extract were due to IgE-allergen reaction. This is the second case of hypersensitivity to ash wood dust reported in the literature.
一名42岁男性报告,在非职业接触白蜡木粉尘时出现呼吸困难发作。对常见变应原和白蜡花粉进行的皮肤点刺试验呈阳性。吸入白蜡木粉尘(激发试验)引发了非常强烈的即刻支气管痉挛反应,伴有大量水样鼻漏、结膜充血和流泪。吸入松木粉尘后未出现这些症状。记录到对白蜡木提取物的皮肤(点刺试验)阳性反应。当患者不再接触白蜡木粉尘时,呼吸困难症状消退,并且观察到支气管对组胺的反应性降低了4倍——PC20从0.53毫克/毫升增加到2.1毫克/毫升(根据科克罗夫特方法)。作者得出结论,吸入白蜡木粉尘后的即刻支气管反应以及对白蜡木提取物的即刻皮肤阳性反应是由IgE-变应原反应引起的。这是文献中报道的第二例对白蜡木粉尘过敏的病例。