Misfeldt M L, Grimm D R
School of Medicine, University of Missouri-Columbia 65212.
Vet Immunol Immunopathol. 1994 Oct;43(1-3):167-75. doi: 10.1016/0165-2427(94)90133-3.
Sinclair swine display cutaneous melanoma lesions and develop a generalized depigmentation subsequent to tumor regression. Sinclair swine represent a valuable animal model to study the factors influencing the development of melanoma and also the factors which lead to the development of vitiligo. Therefore, information obtained in studies of Sinclair swine should facilitate our understanding of the mechanisms by which melanoma and vitiligo develop and provide us with possible therapeutic treatments for these human diseases.
辛克莱猪会出现皮肤黑色素瘤病变，并且在肿瘤消退后会出现全身性色素脱失。辛克莱猪是一种有价值的动物模型，可用于研究影响黑色素瘤发展的因素以及导致白癜风发展的因素。因此，在对辛克莱猪的研究中获得的信息应有助于我们理解黑色素瘤和白癜风的发病机制，并为这些人类疾病提供可能的治疗方法。
