Okunaka T, Kato H
Dept. of Surgery, Tokyo Medical College.
Gan To Kagaku Ryoho. 1995 Feb;22(2):179-84.
Laser endoscopic therapy has now achieved status as an effective treatment modality for lung cancer. The usefulness of Nd-YAG laser as palliative treatment for obstructive tracheobronchial tumors has been recognized. Our experience consisted in 205 YAG laser cases, including 184 obstructive tracheobronchial tumors, and the airway gauge was improved in 88.3%. On the other hand, the effectiveness of photodynamic therapy (PDT) using photofrin as a photosensitizer was demonstrated in our institution in 1979 for the treatment of lung cancers, and increasing attention has focused on this new treatment technique. Over the past decade, 211 patients with central lung cancers, including 66 cases of early-stage lesions, have been treated at Tokyo Medical College Hospital, and a complete remission rate of 65.2% was achieved. We gave an overview of laser endoscopic therapy, including Nd-YAG laser treatment and photodynamic therapy, for lung cancer as well as an evaluation of the effectiveness of these therapies.
激光内镜治疗现已成为肺癌的一种有效治疗方式。钕钇铝石榴石（Nd-YAG）激光作为阻塞性气管支气管肿瘤姑息治疗的有效性已得到认可。我们有205例YAG激光治疗病例的经验，其中包括184例阻塞性气管支气管肿瘤，气道通畅率改善了88.3%。另一方面，1979年我们机构证明了使用光敏剂卟吩姆钠的光动力疗法（PDT）对肺癌治疗的有效性，并且这种新的治疗技术已越来越受到关注。在过去十年中，东京医科大学医院对211例中央型肺癌患者进行了治疗，其中包括66例早期病变患者，完全缓解率达到了65.2%。我们概述了用于肺癌的激光内镜治疗，包括Nd-YAG激光治疗和光动力疗法，以及对这些疗法有效性的评估。
