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[中心型早期肺癌的光动力疗法]

[Photodynamic therapy of centrally located early-stage lung cancer].

作者信息

Furuse K

机构信息

Dept. of Internal Medicine, National Kinki Central Hospital for Chest Diseases.

出版信息

Gan To Kagaku Ryoho. 1996 Jan;23(1):27-30.

PMID:8546465
Abstract

Photodynamic therapy (PDT) with photofrin II and excimer dye laser has an excellent effect on patients (pts) with centrally located early-stage lung cancer with a limited tumor length of 1 cm or less and a clearly visible tumor margin. Further, to expand the therapeutic area of PDT to these early-stage lung cancers, it is necessary to exploit more powerful laser equipment and more sensitive sensitizers. Also, it is essential in the decision to treat early-stage lung cancer to evaluate whether PDT can be used as an effective alternative therapy to surgery in patients with operable centrally located early-stage lung cancer. Finally, it is an important issue for the treatment of centrally located early-stage lung cancer to determine which therapeutic modalities have to be selected as the initial choice in endoscopic therapy.

摘要

使用光敏剂Ⅱ和准分子染料激光进行的光动力疗法(PDT)对肿瘤长度局限于1厘米或更短且肿瘤边缘清晰可见的中央型早期肺癌患者有极佳疗效。此外,为了将PDT的治疗范围扩展至这些早期肺癌,有必要采用更强大的激光设备和更灵敏的光敏剂。而且,在决定治疗早期肺癌时,评估PDT能否作为可手术的中央型早期肺癌患者手术的有效替代疗法至关重要。最后,对于中央型早期肺癌的治疗而言,确定在内镜治疗中必须选择哪些治疗方式作为初始选择是一个重要问题。

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