Ferreira P, Hemerly A, Van Montagu M, Inzé D
Laboratorium voor Genetica, Universiteit Gent, Belgium.
Plant Mol Biol. 1994 Dec;26(5):1289-303. doi: 10.1007/BF00016475.
Knowledge of the control of cell division in eukaryotes has increased tremendously in recent years. The isolation and characterization of the major players from a number of systems and the study of their interactions have led to a comprehensive understanding of how the different components of the cell cycle apparatus are brought together and assembled in a fine-tuned machinery. Many parts of this machine are highly conserved in organisms as evolutionary distant as yeast and animals. Some key regulators of cell division have also been identified in higher plants and have been shown to be functional homologues of the yeast or animal proteins. Although still in its early days, investigations into the regulation of these molecules have provided some clues on how cell division is coupled to plant development.
近年来，我们对真核生物细胞分裂调控的了解有了极大的增长。从多个系统中分离并鉴定出主要参与者，以及对它们相互作用的研究，使我们全面了解了细胞周期机制的不同组成部分是如何组合在一起，并装配成一个精密调节的机器。这台机器的许多部分在进化距离甚远的酵母和动物等生物体中高度保守。在高等植物中也鉴定出了一些细胞分裂的关键调节因子，并且已证明它们是酵母或动物蛋白质的功能同源物。尽管相关研究仍处于早期阶段，但对这些分子调控的研究已经为细胞分裂如何与植物发育相联系提供了一些线索。
