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静脉感染后小鼠李斯特菌病期间单核细胞增生李斯特菌的粪便排出情况

Fecal shedding of Listeria monocytogenes during murine listeriosis after intravenous infection.

作者信息

Nichterlein T, Kretschmar M, Hof H

机构信息

Institute of Medical Microbiology and Hygiene, Faculty of Clinical Medicine Mannheim, University of Heidelberg, Germany.

出版信息

Zentralbl Bakteriol. 1994 Aug;281(2):192-5. doi: 10.1016/s0934-8840(11)80569-4.

Abstract

Female NMRI SPF-Mice were intravenously infected with L. monocytogenes and the feces and urine samples were cultured to detect a possible presence of the bacterium. In 6 out of 10 mice, the bacteria occurred in the feces, but not in the urine samples. Listerial shedding was detected only during acute listeriosis from day 2 to day 9 post infectionem. Thus, listerial shedding after infection via routes other than the gastrointestinal tract is possible not only in newborns, but also in adult experimental animals.

摘要

雌性NMRI无特定病原体(SPF)小鼠经静脉注射感染单核细胞增生李斯特菌,对粪便和尿液样本进行培养以检测细菌的可能存在情况。在10只小鼠中有6只的粪便中发现了细菌,但尿液样本中未发现。仅在感染后第2天至第9天的急性李斯特菌病期间检测到李斯特菌排出。因此,经胃肠道以外途径感染后李斯特菌的排出不仅在新生动物中可能发生,在成年实验动物中也可能发生。

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