Silich V A, Fiks L I, Sokolova M S, Orlova E V, Cherkasskaia R S
Zh Mikrobiol Epidemiol Immunobiol. 1976 Apr(3):40-4.
The authors present materials of the elaboration of a method of obtaining stable erythrocytic diagnostic agents from semipurified preparations of type-specific antigens of the hemolytic streptococcus of the 1st, 4th, 12th and 18th serotypes. Adequate specificity and high sensitivity of the passive hemagglutination test was shown in examination of the sera of experimental animals. In the sera of healthy children the type-specific antibodies were revealed with a different frequency at various seasons of the year; this was in inverse correlation with the level of scarlet fever morbidity.
作者介绍了从1、4、12和18血清型溶血性链球菌的型特异性抗原半纯化制剂中获取稳定红细胞诊断剂方法的研制材料。在对实验动物血清的检测中，被动血凝试验显示出足够的特异性和高灵敏度。在健康儿童的血清中，一年中不同季节以不同频率检测到型特异性抗体；这与猩红热发病率水平呈负相关。
