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[影响脊髓灰质炎疫苗接种效果的因素研究]

[Study on factors affecting vaccination effect of poliomyelitis vaccine].

作者信息

Chai F, Zhang R

机构信息

Institute of Epidemiology and Microbiology, Chinese Academy of Preventive Medicine, Beijing.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 1994 Oct;15(5):267-70.

PMID:7859258
Abstract

We carried out this 1:2 matched case-control study in some counties and townships in Guangxi, Henan and Jiangsu provinces from June to October in 1992 to find the risk factors of poliomyelitis incidence among fully vaccinated children. Then we processed the collected data with individual and multiple condition logistic regression analysis and found the risk factors of poliomyelitis incidence among fully vaccinated children included two kinds, the community factors and the individual factors. The community factors which related to the cold chain and health services. They are the special risk factors for fully vaccinated children. The individual factors are the common risk factors for both fully vaccinated and unvaccinated children. In addition, children received five or more doses of TOPV was a favorable factor against poliomyelitis. It was showed that we must improve vaccination quality while rising TOPV coverage continually.

摘要

1992年6月至10月,我们在广西、河南和江苏的一些县乡开展了这项1:2匹配的病例对照研究,以寻找全程接种儿童中脊髓灰质炎发病的危险因素。然后,我们对收集的数据进行了单因素和多因素条件logistic回归分析,发现全程接种儿童中脊髓灰质炎发病的危险因素包括两类,即社区因素和个体因素。社区因素与冷链和卫生服务有关。它们是全程接种儿童的特殊危险因素。个体因素是全程接种和未接种儿童的共同危险因素。此外,儿童接种5剂及以上的三价口服脊髓灰质炎减毒活疫苗(TOPV)是预防脊髓灰质炎的有利因素。结果表明,在不断提高TOPV接种率的同时,必须提高接种质量。

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