El-Deeb H, El-Rafie M
Gaz Egypt Paediatr Assoc. 1975 Apr;23(2):161-6.
Vaccination against poliomyelitis has been compulsory all over Egypt since 1968. Therefore, it is presumed that all infants and children below six years have already been vaccinated. This study is planned to estimate the magnitude of paralytic poliomyelitis in Egypt after six years compulsory vaccination. The cases studied were investigated with regard to socioeconomic status and history and place of vaccination, association of vomiting and diarrhoea or breast feeding within two hours of vaccination, and blood grouping. These results were compared with those of a control group of non-paralytic cases chosen at random from patients who visited the same hospital. Samples of the vaccine were collected from different centres in which children received vaccination and were titrated to estimate their potency at Agouza Laboratories for Vaccines and Sera. The results revealed that still we have a high incidence of poliomyelitis viz : 985/100,000 out-patients, also males are more affected than females with sex ratio 3:2. Of the paralytic cases 22% had proper vaccination while improper vaccination was found in 78%. There was predominance of blood group O among the paralytic cases. The detailed results and discussion of paralytic cases compared to the control has been also fulfilled. Tiltration of the vaccine revealed a lower than the accepted standard indicating altered potency.
自1968年起，埃及全国实行脊髓灰质炎强制疫苗接种。因此，据推测所有6岁以下婴幼儿均已接种过疫苗。本研究旨在评估在实行六年强制疫苗接种后埃及麻痹性脊髓灰质炎的发病规模。对所研究病例调查了社会经济状况、疫苗接种史及地点、接种疫苗两小时内呕吐腹泻或母乳喂养情况以及血型。将这些结果与从同一家医院就诊患者中随机选取的非麻痹性病例对照组的结果进行比较。从不同儿童接种疫苗的中心采集疫苗样本，并在阿古扎疫苗和血清实验室进行滴定以评估其效力。结果显示，脊髓灰质炎发病率仍然很高，即每10万名门诊患者中有985例，男性比女性更易感染，性别比为3:2。在麻痹性病例中，22%接种情况正常，78%存在接种不当情况。麻痹性病例中O型血占主导。还完成了麻痹性病例与对照组详细结果的比较及讨论。疫苗滴定结果显示低于公认标准，表明效力改变。
