Castell J A, Castell D O, Duranceau C A, Topart P
Department of Medicine, Graduate Hospital, Philadelphia, Pennsylvania 19146.
Dysphagia. 1995 Winter;10(1):22-6. doi: 10.1007/BF00261275.
Improved techniques in esophageal manometry have made this test an attractive option for investigating pharyngeal or esophageal disorders in patients with dysphagia. We studied esophageal as well as upper esophageal sphincter/pharyngeal (UES/P) pressure dynamics in 11 patients with an established diagnosis of oculopharyngeal muscular dystrophy with modern solid-state manometric techniques and then compared manometric and clinical findings. Esophageal manometric abnormalities were found in 10/11 patients, with the most common being simultaneous contractions and incomplete lower esophageal relaxation. 9/11 patients showed abnormal UES/P manometrics, with the most common abnormalities found in the pharynx. The presence of manometric abnormalities closely paralleled clinical assessment of degree of disease severity. Modern manometric techniques offer an opportunity for a quantitative assessment of swallow abnormalities.
食管测压技术的改进使这项检查成为吞咽困难患者咽部或食管疾病研究的一个有吸引力的选择。我们采用现代固态测压技术研究了11例确诊为眼咽型肌营养不良的患者的食管以及食管上括约肌/咽部（UES/P）压力动态变化，然后比较了测压结果和临床发现。11例患者中有10例发现食管测压异常，最常见的是同步收缩和食管下括约肌松弛不完全。11例患者中有9例UES/P测压异常，最常见的异常出现在咽部。测压异常的存在与疾病严重程度的临床评估密切相关。现代测压技术为吞咽异常的定量评估提供了机会。
