Frier M, Perkins A C
Department of Medical Physics, Queens Medical Centre, University Hospital Nottingham NHS Trust, UK.
Eur J Nucl Med. 1994 Nov;21(11):1234-42. doi: 10.1007/BF00182360.
A review is presented of the design of radiolabelled test meals for the evaluation of gastrointestinal function, including oesophageal transit, gastro-oesophageal reflux, gastric emptying, enterogastric reflux and transit through the whole bowel. Descriptions of different systems are presented, together with validations of the procedures used. Published methods for assessment of oesophageal transit show a marked degree of consistency, whereas gastric emptying studies employ a wide range of both liquid and solid test meals. Recommendations are made concerning the optimal system for investigation of each part of the gastrointestinal tract, but whichever system is adopted, it is important to employ some validation procedures, and to establish normal ranges in the population under study.
本文综述了用于评估胃肠功能的放射性标记试验餐的设计，包括食管转运、胃食管反流、胃排空、肠胃反流以及全肠道转运。文中介绍了不同的系统，并对所采用的程序进行了验证。已发表的评估食管转运的方法显示出高度的一致性，而胃排空研究则采用了多种液体和固体试验餐。针对胃肠道各部分的最佳研究系统提出了建议，但无论采用哪种系统，采用一些验证程序并确定所研究人群的正常范围都很重要。
