Jaross W, Assmann G, Bergmann S, Schulte H
Institute of Clinical Chemistry and Laboratory Diagnostics, Medical Academy, Dresden.
Eur J Epidemiol. 1994 Jun;10(3):307-15. doi: 10.1007/BF01719355.
Trend analyses based on WHO statistics for average life expectancy, age-standardized cardiovascular (CVD) morbidity and mortality show significant differences between the former German Democratic Republic (GDR) and the former Federal Republic of Germany (FRG). To investigate whether this is due to a different prevalence of cardiovascular risk factors, the Dresden Cardiovascular Risk and Nutrition (DRECAN) study was conducted using the complete methodology of the Prospective Cardiovascular Münster (PROCAM) study, i.e., the same methods and strict quality controls, with an exchange of specimens between both laboratories. The results were compared with those of an adjusted subpopulation of the PROCAM study. Even before unification there were only small differences in lipoprotein profiles between West and East Germany, 10 months after unification these differences were minimal. The survey does not sufficiently explain the differences in CHD morbidity and mortality between Western and Eastern Germany. Further analyses of the nutritional aspects will show whether the change, in available foodstuffs after unification has led to substantially changed nutritional habits, and whether this might explain some of the results.
基于世界卫生组织关于平均预期寿命、年龄标准化心血管疾病（CVD）发病率和死亡率的统计数据进行的趋势分析显示，前德意志民主共和国（GDR）和前德意志联邦共和国（FRG）之间存在显著差异。为了调查这是否是由于心血管危险因素的不同患病率所致，德累斯顿心血管风险与营养（DRECAN）研究采用了前瞻性心血管明斯特（PROCAM）研究的完整方法，即相同的方法和严格的质量控制，并在两个实验室之间交换样本。将结果与PROCAM研究的一个经过调整的亚组的结果进行了比较。甚至在统一之前，西德和东德之间的脂蛋白谱差异就很小，统一10个月后这些差异微乎其微。该调查不足以解释德国西部和东部之间冠心病发病率和死亡率的差异。对营养方面的进一步分析将表明，统一后可获得的食品的变化是否导致了营养习惯的大幅改变，以及这是否可以解释部分结果。
