Grases F, Melero G, Costa-Bauzá A, Prieto R, March J G
Department of Chemistry, University of Balearic Islands, Palma de Mallorca, Spain.
Int Urol Nephrol. 1994;26(5):507-11. doi: 10.1007/BF02767650.
The effects of seven plants with suspected application to prevent and treat stone kidney formation (Verbena officinalis, Lithospermum officinale, Taraxacum officinale, Equisetum arvense, Arctostaphylos uva-ursi, Arctium lappa and Silene saxifraga) have been studied using female Wistar rats. Variations of the main urolithiasis risk factors (citraturia, calciuria, phosphaturia, pH and diuresis) have been evaluated. It can be concluded that beneficial effects caused by these herb infusions on urolithiasis can be attributed to some disinfectant action, and tentatively to the presence of saponins. Specifically, some solvent action can be postulated with respect to uric stones or heterogeneous uric nucleus, due to the basifying capacity of some herb infusions. Nevertheless, for all the mentioned beneficial effects, more effective and equally innocuous substances are well known.
使用雌性Wistar大鼠研究了七种疑似具有预防和治疗肾结石形成作用的植物（马鞭草、药用紫草、蒲公英、问荆、熊果、牛蒡和石生蝇子草）的效果。评估了主要尿路结石风险因素（枸橼酸尿、钙尿、磷尿、pH值和利尿）的变化。可以得出结论，这些草药浸液对尿路结石产生的有益作用可归因于某种消毒作用，并初步归因于皂苷的存在。具体而言，由于某些草药浸液的碱化能力，对于尿酸结石或异质尿酸核，可以假定存在某种溶剂作用。然而，对于所有上述有益作用，已知有更有效且同样无害的物质。
