无需开颅手术诊断放射敏感性下丘脑肿瘤：颅内非典型畸胎瘤的内分泌和神经放射学研究

Diagnosis of radiosensitive hypothalamic tumors without craniotomy: endocrine and neuroradiologic studies of intracranial atypical teratomas.

作者信息

Spiegel A M, Di Chiro G, Gorden P, Ommaya A K, Kolins J, Pomeroy T C

出版信息

Ann Intern Med. 1976 Sep;85(3):290-3. doi: 10.7326/0003-4819-85-3-290.

Abstract

Three patients with intracranial atypical teratomas presented with symptoms of endocrine dysfunction (diabetes insipidus, hyperprolactinemia, and anterior hypopituitarism) suggestive of a hypothalamic disorder. Computer-assisted tomography done in two of the three cases enabled us to document the presence of a mass and institute radiotherapy, without prior neurosurgical exploration. Computer-assisted tomography also provided a safe and effective method of assessing the effects of radiotherapy.

摘要

三名患有颅内非典型畸胎瘤的患者出现内分泌功能障碍症状（尿崩症、高催乳素血症和垂体前叶功能减退），提示下丘脑疾病。在这三例中的两例进行了计算机断层扫描，使我们能够记录肿块的存在并进行放射治疗，而无需事先进行神经外科探查。计算机断层扫描还提供了一种安全有效的评估放射治疗效果的方法。