Gutiérrez-Calzada J L, Ramos-Titos J, González-Bonilla J A, Garcia-Vaquero A S, Martin-Morales A, Burgos-Rodríguez R
Department of Urology, Hospital Regional de Málaga, Spain.
J Urol. 1995 Mar;153(3 Pt 1):612-4. doi: 10.1097/00005392-199503000-00015.
Six patients in this series of 543 renal transplants (1.10%) suffered a post-transplant renal segmental infarct of the donor kidney because of occlusion of an accessory renal artery. Five grafted kidneys had multiple renal arteries. Patients presented with symptoms of a caliceal fistula and were treated by partial (25 to 40%) transplant nephrectomy, followed by closure and tissue coverage with either parietal peritoneum (4 patients) or lyophilized human dura mater sealed with fibrin (2). In 2 cases the renal ischemia and necrosis involved the ureter, and a pyelo-pyelostomy was performed. One patient died of cardiorespiratory complications immediately postoperatively. Five years postoperatively all kidneys functioned well without recurrence of fistula and 5 patients returned to a normal life-style. The combination of radical excision and tissue closure, plus ureteral substitution when needed was an effective treatment that prevented loss of the graft.
在这543例肾移植系列中,有6例患者(1.10%)因副肾动脉闭塞而发生移植后供肾节段性梗死。5例移植肾有多个肾动脉。患者出现肾盂瘘症状,接受了部分(25%至40%)移植肾切除术治疗,随后用壁层腹膜(4例患者)或用纤维蛋白密封的冻干人硬脑膜进行封闭和组织覆盖(2例)。2例患者的肾缺血和坏死累及输尿管,进行了肾盂-肾盂吻合术。1例患者术后立即死于心肺并发症。术后5年,所有肾脏功能良好,瘘管未复发,5例患者恢复了正常生活方式。根治性切除与组织封闭相结合,必要时进行输尿管替代是一种有效的治疗方法,可防止移植肾丢失。